Medical Clinic 1 - Gastroenterology, Pneumology and Endocrinology, Erlangen University Hospital

Professional career
Since 2017: Head of the Hector Centre for Nutrition, Exercise and Sport, Medical Clinic 1, University Hospital Erlangen
since 2010: Head of the Nutrition Team, Medical Clinic 1, University Hospital Erlangen
2006 - 2010: Deputy Head of the Nutrition Team, Medical Clinic, University Hospital Erlangen
since 2003: Physician, Medical Clinic 1, University Hospital Erlangen

Academic career
2013: Endowed professorship for Clinical and Experimental Nutritional Medicine, Medical Clinic 1, University Hospital Erlangen
2011: Habilitation in internal medicine

Education
1996 - 2002: Medical studies, Friedrich-Alexander University Erlangen-Nuremberg
1995: Obtained university entrance qualification

Further qualifications
2022 Additional qualification in nutritional medicine
10/2013 Specialist in gastroenterology
10/2010 Specialist in Internal Medicine
2007 Additional qualification in nutritional medicine according to DGEM Member of the expert group for the guidelines on coeliac disease and inflammatory bowel diseases
Expert for short bowel syndrome and gastrointestinal diseases in the Centre for Rare Diseases of the UK Erlangen

Research profile
Tumour cachexia syndrome
Chronic inflammatory bowel diseases
Coeliac disease
Food intolerances and allergies
Irritable bowel syndrome
Microbiome and immunopathogenesis

Memberships
German Society for Nutritional Medicine (DGEM)
German Society of Internal Medicine (DGIM)
German Society for Mucosal Immunology and Microbiome (DGMIM) - Secretary
German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS)
German-Turkish Medical Society of Bavaria e. V. (DTM)
Numeas - Association for Nutritional Medicine and Exercise & Sport in Cancer e. V. - Chairperson

Link to Yurdagül Zopf >>>

Bittner DO, Goeller M, Dey D, Zopf Y, Achenbach S, Marwan M. High levels of eicosapentaenoic acid are associated with lower pericoronary adipose tissue attenuation as measured by coronary CTA. Atherosclerosis. 2020 Oct 10:S0021-9150(20)30569-4.

Bittner DO, Goeller M, Zopf Y, Achenbach S, Marwan M. Early-onset coronary atherosclerosis in patients with low levels of omega-3 fatty acids. Eur J Clin Nutr. 2020 Apr;74(4):651-656.

Catassi C, Alaedini A, Bojarski C, Bonaz B, Bouma G, Carroccio A, Castillejo G, De Magistris L, Dieterich W, Di Liberto D, Elli L, Fasano A, Hadjivassiliou M, Kurien M, Lionetti E, Mulder CJ, Rostami K, Sapone A, Scherf K, Schuppan D, Trott N, Volta U, Zevallos V, Zopf Y, Sanders DS. The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update. Nutrients. 2017 Nov; 9(11): 1268.

Dieterich W, Neurath MF, Zopf Y. Intestinal ex vivo organoid culture reveals altered programmed crypt stem cells in patients with celiac disease. Sci Rep. 2020 Feb 26;10(1):3535.

Dieterich W, Schink M, Zopf Y. Microbiota in the Gastrointestinal Tract. Med Sci (Basel) 2018 Dec; 6(4): 116.

Dieterich W, Schuppan D, Schink M, Schwappacher R, Wirtz S, Agaimy A, Neurath MF, Zopf Y. Influence of low FODMAP and gluten-free diets on disease activity and intestinal microbiota in patients with non-celiac gluten sensitivity. Clin Nutr. 2019 Apr;38(2):697-707.

Dieterich W, Tietz E, Kohl M, Konturek PC, Rath T, Neurath MF, Zopf Y. Food Intolerance of Unknown Origin: Caused by Mucosal Inflammation? A Pilot Study. Clin Transl Gastroenterol. 2021 Feb 17;12(2):e00312.

Dieterich W, Zopf Y. Gluten and FODMAPS—Sense of a Restriction/When Is Restriction Necessary? Nutrients. 2019 Aug; 11(8): 1957.

Felber J, Bläker H, Fischbach W, Koletzko S, Laaß M, Lachmann N, Lorenz P, Lynen P, Reese I, Scherf K, Schuppan D, Schumann M, Aust D, Baas S, Beisel S, de Laffolie J, Duba E, Holtmeier W, Lange L, Loddenkemper C, Moog G, Rath T, Roeb E, Rubin D, Stein J, Török H, Zopf Y. ktualisierte S2k-Leitlinie Zöliakie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS). Z Gastroenterol. 2022 May;60(5):790-856. doi: 10.1055/a-1741-5946.

Gingrich A, Volkert D, Kiesswetter E, Thomanek M, Bach S, Sieber CC, Zopf Y. Prevalence and overlap of sarcopenia, frailty, cachexia and malnutrition in older medical inpatients. BMC Geriatr. 2019; 19: 120.

Konturek P, Konturek K, Zopf Y, Harsch IA [Intestinal microbiota - a vital "organ" with manifold functions]. MMW Fortschr Med. 2020 Mar;162(Suppl 4):9-14.

Konturek PC, Harsch IA, Konturek K, Schink M, Konturek T, Neurath MF, Zopf Y. Gut–Liver Axis: How Do Gut Bacteria Influence the Liver? Med Sci (Basel) 2018 Sep; 6(3): 79.

Konturek PC, Harsch IA, Neurath MF, Zopf Y. COVID-19 - more than respiratory disease: a gastroenterologist's perspective. J Physiol Pharmacol. 2020 Apr;71(2).

Konturek PC, Konturek K, Brzozowski T, Wojcik D, Magierowski M, Targosz A, Krzysiek-Maczka G, Sliwowski Z, Strzalka M, Magierowska K, Szczyrk U, Kwiecien S, Ptak-Belowska A, Neurath M, Dieterich W, Wirtz S, Zopf Y. Participation of the intestinal microbiota in the mechanism of beneficial effect of treatment with synbiotic Syngut on experimental colitis under stress conditions. J Physiol Pharmacol. 2020 Jun;71(3).

Konturek PC, Konturek K, Zopf Y. [Stress and inflammatory bowel disease]. MMW Fortschr Med. 2020 Jul;162(Suppl 5):3-6.

Konturek PC, Zopf Y. [Therapeutic modulation of intestinal microbiota in irritable bowel syndrome. From probiotics to fecal microbiota therapy]. MMW Fortschr Med. 2017 Dec;159(Suppl 7):1-5.

Orlemann T, Reljic D, Zenker B, Meyer J, Eskofier B, Thiemt J, Herrmann HJ, Neurath MF, Zopf Y. A Novel Mobile Phone App (OncoFood) to Record and Optimize the Dietary Behavior of Oncologic Patients: Pilot Study. JMIR Cancer. 2018 Jul-Dec; 4(2): e10703.

Pinzer TC, Tietz E, Waldmann E, Schink M, Neurath MF, Zopf Y. Circadian profiling reveals higher histamine plasma levels and lower diamine oxidase serum activities in 24% of patients with suspected histamine intolerance compared to food allergy and controls. Allergy. 2018 Apr; 73(4): 949–957.

Rath T, Dieterich W, Kätscher-Murad C, Neurath MF, Zopf Y. Cross-sectional imaging of intestinal barrier dysfunction by confocal laser endomicroscopy can identify patients with food allergy in vivo with high sensitivity. Sci Rep. 2021 Jun 17;11(1):12777.

Reljic D, Dieterich W, Herrmann HJ, Neurath MF, Zopf Y. "HIIT the Inflammation": Comparative Effects of Low-Volume Interval Training and Resistance Exercises on Inflammatory Indices in Obese Metabolic Syndrome Patients Undergoing Caloric Restriction. Nutrients. 2022 May 10;14(10):1996. doi: 10.3390/nu14101996.

Reljic D, Frenk F, Herrmann HJ, Neurath MF, Zopf Y. Effects of very low volume high intensity versus moderate intensity interval training in obese metabolic syndrome patients: a randomized controlled study. Sci Rep. 2021 Feb 2;11(1):2836.

Reljic D, Frenk F, Herrmann HJ, Neurath MF, Zopf Y. Low-volume high-intensity interval training improves cardiometabolic health, work ability and well-being in severely obese individuals: a randomized-controlled trial sub-study. J Transl Med. 2020 Nov 7;18(1):419.

Reljic D, Herrmann HJ, Jakobs B, Dieterich W, Mougiakakos D, Neurath MF, Zopf Y. Feasibility, Safety, and Preliminary Efficacy of Very Low-volume Interval Training in Advanced Cancer Patients. Med Sci Sports Exerc. 2022 Jul 7. doi: 10.1249/MSS.0000000000002989.

Reljic D, Herrmann HJ, Neurath MF, Zopf Y. Iron Beats Electricity: Resistance Training but Not Whole-Body Electromyostimulation Improves Cardiometabolic Health in Obese Metabolic Syndrome Patients during Caloric Restriction-A Randomized-Controlled Study. Nutrients. 2021 May 13;13(5):1640.

Reljic D, Konturek PC, Herrmann HJ, Neurath MF, Zopf Y. Effects of whole-body electromyostimulation exercise and caloric restriction on cardiometabolic risk profile and muscle strength in obese women with the metabolic syndrome: a pilot study. J Physiol Pharmacol. 2020 Feb;71(1).

Reljic D, Konturek PC, Herrmann HJ, Siebler J, Neurath MF, Zopf Y. Very low-volume interval training improves nonalcoholic fatty liver disease fibrosis score and cardiometabolic health in adults with obesity and metabolic syndrome. J Physiol Pharmacol. 2021 Dec;72(6). doi: 10.26402/jpp.2021.6.10.

Reljic D, Lampe D, Wolf F, Zopf Y, Herrmann HJ, Fischer J. Prevalence and predictors of dropout from high-intensity interval training in sedentary individuals: A meta-analysis. Scand J Med Sci Sports. 2019 Sep;29(9):1288-1304.

Reljic D, Zarafat D, Jensen B, Herrmann HJ, Neurath MF, Konturek PC, Zopf Y. Phase angle and vector analysis from multifrequency segmental bioelectrical impedance analysis: new reference data for older adults. J Physiol Pharmacol. 2020 Aug;71(4).

Rostami K, Bold J, Ismail Ali J, Parr A, Dieterich W, Zopf Y, Htoo A, Rostami-Nejad M, Danciu M. An algorithm for differentiating food antigen-related gastrointestinal symptoms. Gastroenterol Hepatol Bed Bench. 2021 Winter;14(1):8-16.

Schalk P, Kohl M, Herrmann HJ, Schwappacher R, Rimmele ME, Buettner A, Siebler J, Neurath MF, Zopf Y. Influence of cancer and acute inflammatory disease on taste perception: a clinical pilot study. Support Care Cancer. 2018; 26(3): 843–851. Correction in: Support Care Cancer. 2020 May;28(5):2431.

Schink K, Gaßner H, Reljic D, Herrmann HJ, Kemmler W, Schwappacher R, Meyer J, Eskofier BM, Winkler J, Neurath MF, Klucken J, Zopf Y. Assessment of gait parameters and physical function in patients with advanced cancer participating in a 12-week exercise and nutrition programme: A controlled clinical trial. Eur J Cancer Care (Engl). 2020 Mar;29(2):e13199.

Schink K, Herrmann HJ, Schwappacher R, Meyer J, Orlemann T, Waldmann E, Wullich B, Kahlmeyer A, Fietkau R, Lubgan D, Beckmann MW, Hack C, Kemmler W, Siebler J, Neurath MF, Zopf Y. Effects of whole-body electromyostimulation combined with individualized nutritional support on body composition in patients with advanced cancer: a controlled pilot trial. BMC Cancer. 2018; 18: 886.

Schink K, Reljic D, Herrmann HJ, Meyer J, Mackensen A, Neurath MF, Zopf Y. Whole-Body Electromyostimulation Combined With Individualized Nutritional Support Improves Body Composition in Patients With Hematological Malignancies – A Pilot Study. Front Physiol. 2018; 9: 1808.

Schink M, Konturek PC, Herbert SL, Renner SP, Burghaus S, Blum S, Fasching PA, Neurath MF, Zopf Y. Different nutrient intake and prevalence of gastrointestinal comorbidities in women with endometriosis. J Physiol Pharmacol. 2019 Apr;70(2).

Schink M, Konturek PC, Tietz E, Dieterich W, Pinzer TC, Wirtz S, Neurath MF, Zopf Y. Microbial patterns in patients with histamine intolerance. J Physiol Pharmacol. 2018 Aug;69(4).

Schuppan D, Mäki M, Lundin KEA, Isola J, Friesing-Sosnik T, Taavela J, Popp A, Koskenpato J, Langhorst J, Hovde Ø, Lähdeaho ML, Fusco S, Schumann M, Török HP, Kupcinskas J, Zopf Y, Lohse AW, Scheinin M, Kull K, Biedermann L, Byrnes V, Stallmach A, Jahnsen J, Zeitz J, Mohrbacher R, Greinwald R; CEC-3 Trial Group. A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease. N Engl J Med. 2021 Jul 1;385(1):35-45.

Schwappacher R, Dieterich W, Reljic D, Pilarsky C, Mukhopadhyay D, Chang DK, Biankin AV, Siebler J, Herrmann HJ, Neurath MF, Zopf Y. Muscle-Derived Cytokines Reduce Growth, Viability and Migratory Activity of Pancreatic Cancer Cells. Cancers (Basel). 2021 Jul 29;13(15):3820.

Schwappacher R, Schink K, Sologub S, Dieterich W, Reljic D, Friedrich O, Herrmann HJ, Neurath MF, Zopf Y. Physical activity and advanced cancer: evidence of exercise-sensitive genes regulating prostate cancer cell proliferation and apoptosis. J Physiol. 2020 Sep;598(18):3871-3889.

Sturm A, Atreya R, Bettenworth D, Bokemeyer B, Dignaß A, Ehehalt R, Germer C, Grunert PC, Helwig U, Herrlinger K, Kienle P, Kreis ME, Kucharzik T, Langhorst J, Maaser C, Ockenga J, Ott C, Siegmund B, Zeißig S, Stallmach A; Collaborators:. Aktualisierte S3-Leitlinie „Diagnostik und Therapie des Morbus Crohn“ der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) – August 2021 – AWMF-Registernummer: 021-004. Z Gastroenterol. 2022 Mar;60(3):332-418. doi: 10.1055/a-1713-3941.

Zopf Y, Reljic D, Dieterich W. Dietary Effects on Microbiota-New Trends with Gluten-Free or Paleo Diet. Med Sci (Basel). 2018 Oct 18;6(4):92.

Zopf Y, Reljic D, Dieterich W. Dietary Effects on Microbiota—New Trends with Gluten-Free or Paleo Diet. Med Sci (Basel) 2018 Dec; 6(4): 92.

Zopf Y, Schink K, Reljic D, Herrmann HJ, Dieterich W, Kiesswetter E, Sieber CC, Neurath MF, Volkert D. Assessing cachexia in older patients: Different definitions - But which one is the most practical for clinical routine? Arch Gerontol Geriatr. 2020 Jan-Feb;86:103943.